Mizutani Laboratory

Publications

• Rino Saiga, Kaede Shiga, Yo Maruta, Chie Inomoto, Hiroshi Kajiwara, Naoya Nakamura, Yu Kakimoto, Yoshiro Yamamoto, Masahiro Yasutake, Masayuki Uesugi, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Viktor Nikitin, Vincent De Andrade, Francesco De Carlo, Yuichi Yamashita, Masanari Itokawa, Soichiro Ide, Kazutaka Ikeda, *Ryuta Mizutani (2024). Murine AI excels at cats and cheese: Structural differences between human and mouse neurons and their implementation in generative AIs. arXiv GitHub repo
• *Ryuta Mizutani, Rino Saiga, Yoshiro Yamamoto, Masayuki Uesugi, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Vincent De Andrade, Francesco De Carlo, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Youta Torii, Itaru Kushima, Shuji Iritani, Norio Ozaki, Kenichi Oshima, Masanari Itokawa, and Makoto Arai (2023). Structural aging of human neurons is opposite of the changes in schizophrenia. PLoS ONE 18(6), e0287646. journal DOI
• *Ryuta Mizutani, Senta Noguchi, Rino Saiga, Yuichi Yamashita, Mitsuhiro Miyashita, Makoto Arai, and Masanari Itokawa (2022). Schizophrenia-mimicking layers outperform conventional neural network layers. Front. Neurorobot. 16, 851471. DOI Journal GitHub
• Rino Saiga, Masayuki Uesugi, Akihisa Takeuchi, Kentaro Uesugi, Yoshio Suzuki, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Youta Torii, Itaru Kushima, Shuji Iritani, Norio Ozaki, Kenichi Oshima, Masanari Itokawa, Makoto Arai, and *Ryuta Mizutani (2021). Brain capillary structures of schizophrenia cases and controls show a correlation with their neuron structures. Sci. Rep. 11, 11768. DOI pdf. News releases: Tokyo Metropolitan Institute of Medical Science SPring-8
• *Ryuta Mizutani, Rino Saiga, Yoshiro Yamamoto, Masayuki Uesugi, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Vincent De Andrade, Francesco De Carlo, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Youta Torii, Itaru Kushima, Shuji Iritani, Norio Ozaki, Kenichi Oshima, Masanari Itokawa, and Makoto Arai (2021). Structural diverseness of neurons between brain areas and between cases. Transl. Psychiatry 11, 49. DOI pdf. News releases: Argonne Natl Lab APS highlights TMIMS SPring-8. [Ranked top 1 percentile with Altmetrics]
• *糸川昌成，堀内泰江，宮下光弘，鳥海和也，鈴木一浩，江越正敏，吉川茜，水谷隆太，新井誠 (2020). 精神症状と病因の非対応 精神科 36(1), 77-85. [invited, Japanese]
• Masanari Itokawa, Kenichi Oshima, Makoto Arai, Youta Torii, Itaru Kushima, Shuji Iritani, Norio Ozaki, Rino Saiga, and *Ryuta Mizutani (2020). Cutting edge morphological studies of postmortem brains of patients with schizophrenia and potential applications of X-ray nanotomography (nano-CT). Psychiatry Clin. Neurosci. 74(3), 176-182. DOI PubMed Japanese abstract JpnAbstDOI
• *糸川昌成，堀内泰江，宮下光弘，鳥海和也，鈴木一浩，江越正敏，吉川茜，水谷隆太，新井誠 (2020). 精神疾患の原因追及とエビデンスについて：斉一性と標準化 精神科治療学 35(2), 177-185. [invited, Japanese]
• Rino Saiga, *Ryuta Mizutani, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Youta Torii, Itaru Kushima, Shuji Iritani, Norio Ozaki, Masanari Itokawa, Kenichi Oshima, and Makoto Arai (2019). Structures of neurons differ between individuals and those differences become extraordinary in schizophrenia. 神経細胞の形の個人差と統合失調症脳での構造変化. Japanese Journal of Molecular Psychiatry 分子精神医学 19(4), 244-247. [invited, Japanese]
• Hideshi Yokoyama, Ryuta Mizutani, Shuji Noguchi and *Naoki Hayashida (2019). Structural and biochemical basis of the formation of isoaspartate in the complementarity-determining region of antibody 64M-5 Fab. Sci. Rep. 9, 18494. DOI PubMed PDB6KDH PDB6KDI
• *Masanari Itokawa, Kenichi Oshima, Makoto Arai, Youta Torii, Itaru Kushima, Shuji Iritani, Norio Ozaki,Rino Saiga, and Ryuta Mizutani (2019). Structural alteration of neurons in schizophrenia - Geometry of brain tissue. 放射光ナノトモグラフィ法を用いた統合失調症における神経細胞の構造変化の解析 - 脳組織の幾何学. Psychiatria et Neurologia Japonica 精神神経学雑誌 121(12), 926-940. [Japanese] Journal site
• Rino Saiga, Vincent De Andrade, Francesco De Carlo, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Youta Torii, Itaru Kushima, Shuji Iritani, Norio Ozaki, Kenichi Oshima, Masanari Itokawa, Makoto Arai, and *Ryuta Mizutani (2019). Nanometer-scale structures of neurons differ between individuals and those differences become extraordinary in schizophrenia. Microsc. Microanal. 25(S2), 1344-1345. DOI pdf
• Rino Saiga, Masato Hoshino, Akihisa Takeuchi, Kentaro Uesugi, Katsuko Naitou, Akemi Kamijo, Noboru Kawabe, Masato Ohtsuka, Shunya Takizawa, and *Ryuta Mizutani (2019). Synchrotron radiation microtomography of brain hemisphere and spinal cord of a mouse model of multiple sclerosis revealed a correlation between capillary dilation and clinical score. J. Comp. Neurol. 527(13), 2091-2100. [invited] DOI arXiv PubMed
• *Ryuta Mizutani, Rino Saiga, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Vincent De Andrade, Francesco De Carlo, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Itaru Kushima, Shuji Iritani, Norio Ozaki, Soichiro Ide, Kazutaka Ikeda, Kenichi Oshima, Masanari Itokawa, and Makoto Arai (2019). Three-dimensional alteration of neurites in schizophrenia. Transl. Psychiatry 9, 85. DOI pdf arXiv
• Hideshi Yokoyama, Ryuta Mizutani, Shuji Noguchi and Naoki Hayashida (2019). Structures of the 64M-5 antibody Fab and its complex with dT(6-4)T indicate induced-fit and high-affinity mechanisms. Acta Cryst. F75, 80-88. DOI
• *Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Vincent De Andrade, Francesco De Carlo, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada and Yoshio Suzuki (2018). Spatial resolution of pre-reconstruction raw images and their nano-CT slices. Microsc. Microanal. 24(S2), 358-359. DOI pdf
• Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Masato Hoshino, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki and *Ryuta Mizutani (2018). Synchrotron radiation nanotomography of biological soft tissues. Microsc. Microanal. 24(S2), 360-361. DOI pdf
• Rino Saiga and *Ryuta Mizutani (2018). Preparation of soft tissue samples for synchrotron radiation microtomography and nanotomography. Protocol Exchange DOI: 10.1038/protex.2018.085. web DOI
• Rino Saiga and *Ryuta Mizutani (2018). Toxicity of visible light follows a rule similar to that for x-ray damage. Microscopy Today 26(2), 58. DOI pdf
• Rino Saiga, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki and *Ryuta Mizutani (2018). Method for estimating modulation transfer function from sample images. Micron 105, 64-69. DOI arXiv
• *Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada and Yoshio Suzuki (2017). Estimating the resolution of real images. J. Phys. Conf. Ser. 849, 012042. DOI pdf arXiv
• *Ryuta Mizutani, Rino Saiga, Masato Ohtsuka, Hiromi Miura, Masato Hoshino, Akihisa Takeuchi and Kentaro Uesugi (2016). Three-dimensional X-ray visualization of axonal tracts in mouse brain hemisphere. Sci. Rep. 6, 35061. DOI pdf arXiv
• Rino Saiga, *Ryuta Mizutani, Chie Inomoto, Susumu Takekoshi, Naoya Nakamura, Akio Tsuboi, Motoki Osawa, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Kentaro Uesugi, Akihisa Takeuchi, Yasuko Terada and Yoshio Suzuki (2016). Three-dimensional structure of brain tissue at submicrometer resolution. AIP Conf. Proc. 1696, 020004. DOI American Institute of Physics
• *Yoshio Suzuki, Akihisa Takeuchi, Yasuko Terada, Kentaro Uesugi and Ryuta Mizutani (2016). Recent progress of hard x-ray imaging microscopy and microtomography at BL37XU of SPring-8. AIP Conf. Proc. 1696, 020013. DOI American Institute of Physics
• *Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Masanari Itokawa, Makoto Arai, Kenichi Oshima, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada and Yoshio Suzuki (2016). A method for estimating spatial resolution of real image in the Fourier domain. J. Microscopy 261(1), 57-66. DOI PubMed arXiv
• *Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Makoto Arai, Akihisa Takeuchi and Yoshio Suzuki (2015). Scanning brain networks with micro-CT. Microscopy Today 23(5), 12-17. Microscopy Today (Microscopy Society of America) DOI pdf [Feature article, invited]
• *Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Makoto Arai, Akihisa Takeuchi and Yoshio Suzuki (2015). X-ray tomographic microscopy of Drosophila brain network and skeletonized model building in the three-dimensional image. Microsc. Microanal. 21(S3), 917-918. DOI pdf
• Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Akio Tsuboi, Motoki Osawa, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Kentaro Uesugi, Akihisa Takeuchi, Yasuko Terada, Yoshio Suzuki and *Ryuta Mizutani (2015). Three-dimensional neuronal structure of human cerebral cortex determined by synchrotron-radiation microtomography. Microsc. Microanal. 21(S3), 919-920. DOI pdf
• *Masato Ohtsuka, Hiromi Miura, Keiji Mochida, Michiko Hirose, Ayumi Hasegawa, Atsuo Ogura, Ryuta Mizutani, Minoru Kimura, Ayako Isotani, Masahito Ikawa, Masahiro Sato and Channabasavaiah B Gurumurthy (2015). One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT). BMC Genomics 16(1), 274. DOI PubMed
• *Ryuta Mizutani, Rino Saiga, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada and Yoshio Suzuki (2014). Analysis of neuronal circuit network by using synchrotron radiation at SPring-8. SPring-8放射光による神経回路ネットワークの解析. Kenbikyo 顕微鏡 49(3), 222-225. pdf The Japanese Society of Microscopy [invited, Japanese]
• *Hideshi Yokoyama and Ryuta Mizutani (2014). Structural biology of DNA (6-4) photoproducts formed by ultraviolet radiation and interactions with their binding proteins. Int. J. Mol. Sci. 15(11), 20321-20338. DOI PubMed
• *Ryuta Mizutani, Yusuke Shimizu, Rino Saiga, Go Ueno, Yuki Nakamura, Akihisa Takeuchi, Kentaro Uesugi and Yoshio Suzuki (2014). Spatiotemporal development of soaked protein crystal. Sci. Rep. 4, 5731. DOI PubMed PDB3WPJ PDB3WU7 PDB3WPK PDB3WU8 PDB3WU9 PDB3WPL PDB3WUA
• *Ryuta Mizutani, Rino Saiga, Akihisa Takeuchi, Kentaro Uesugi and Yoshio Suzuki (2013). Three-dimensional network of Drosophila brain hemisphere. J. Struct. Biol. 184(2), 271-279. DOI PubMed arXiv
• *Ryuta Mizutani and Rino Saiga (2013). Determination of neuronal circuit of human cerebral cortex by using X-ray microtomography. Ｘ線マイクロトモグラフィ法によるヒト大脳神経回路の決定. J. Jpn. Soc. Synchrotron Radiat. Res. 放射光 26(5), 268-275. JSSRR (a revision in English: SPring-8 Information 19(3), 225-229 html) [invited, Japanese]
• *Ryuta Mizutani, Keisuke Taguchi, Masato Ohtsuka, Minoru Kimura, Akihisa Takeuchi, Kentaro Uesugi and Yoshio Suzuki (2013). X-ray microtomographic visualization of Escherichia coli by metalloprotein overexpression. J. Synchrotron Radiation 20(4), 581-586. DOI arXiv
• *Hideshi Yokoyama, Ryuta Mizutani and Yoshinori Satow (2013). Structure of a double-stranded DNA (6-4) photoproduct in complex with the 64M-5 antibody Fab. Acta Crystallographica D69, 504-512. DOI PubMed
• *Yosuke Masuda, Yasushi Nitanai, Ryuta Mizutani and Shuji Noguchi (2013). Crystal structure of 6-guanidinohexanoyl trypsin near the optimum pH reveals the acyl-enzyme intermediate to be deacylated. Proteins 81(3), 526-530. DOI PubMed
• *Hideshi Yokoyama, Ryuta Mizutani, Yoshinori Satow, Kousuke Sato, Yasuo Komatsu, Eiko Ohtsuka and Osamu Nikaido (2012). Structure of the DNA (6-4) photoproduct dTT(6-4)TT in complex with the 64M-2 antibody Fab fragment implies increased antibody-binding affinity by the flanking nucleotides. Acta Crystallographica D68, 232-238. DOI PubMed
• *Ryuta Mizutani and Yoshio Suzuki (2012). X-ray Microtomography in biology. Micron 43(2-3), 104-115. DOI PubMed arXiv [Review, invited]
• *Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, Naoya Nakamura and Yoshio Suzuki (2011). Building human brain network in 3D coefficient map determined by X-ray microtomography. AIP Conference Proceedings 1365, 403-406. AIP
• *Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, R. Yoshiyuki Osamura and Yoshio Suzuki (2010). Unveiling 3D Biological Structures by X-ray Microtomography. In Microscopy: Science, Technology, Applications and Education. Vol. 1, eds. Mendez-Vilas, A. & Diaz Alvarez, J., Badajoz, Formatex Research Centre, pp. 379-386. Review. pdf (2.3 MB) [invited]
• *Ryuta Mizutani, Keisuke Taguchi, Akihisa Takeuchi, Kentaro Uesugi and Yoshio Suzuki (2010). Estimation of presampling modulation transfer function in synchrotron radiation microtomography. Nuclear Instrum. Meth. A 621(1-3), 615-619. DOI arXiv
• *Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, R. Yoshiyuki Osamura and Yoshio Suzuki (2010). Microtomographic analysis of neuronal circuits of human brain. Cerebral Cortex 20(7), 1739-1748. DOI PubMed pdf
• *Ryuta Mizutani, Akihisa Takeuchi, R. Yoshiyuki Osamura, Susumu Takekoshi, Kentaro Uesugi and Yoshio Suzuki (2010). Submicrometer tomographic resolution examined using a micro-fabricated test object. Micron 41(1), 90-95. DOI PubMed arXiv
• *Ryuta Mizutani, Akihisa Takeuchi, Susumu Takekoshi, R. Yoshiyuki Osamura, Kentaro Uesugi and Yoshio Suzuki (2009). Three-dimensional cellular and subcellular structures of human brain tissue determined by microtomography. Journal of Physics: Conference Series 186, 012108. DOI pdf
• *Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, R. Yoshiyuki Osamura and Yoshio Suzuki (2009). Three-dimensional microstructural analysis of human brain tissue by using synchrotron radiation microtomographs. In Handbook on White Matter: Structure, Function and Changes, eds. Westland, T.B. & Calton, R.N., New York, Nova Science Publishers, pp. 247-277. Review. pdf (9.5 MB) Amazon [invited]
• *Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi and Yoshio Suzuki (2008). Evaluation of the improved three-dimensional resolution of a synchrotron radiation computed tomograph using a micro-fabricated test pattern. J. Synchrotron Radiation 15(6), 648-654. DOI PubMed pdf
• *Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, R. Yoshiyuki Osamura and Yoshio Suzuki (2008). X-ray microtomographic imaging of three-dimensional structure of soft tissues. Tissue Engineering Part C 14(4), 359-363. DOI PubMed pdf
• *Ryuta Mizutani, Akihisa Takeuchi, Genta Akamatsu, Kentaro Uesugi and Yoshio Suzuki (2008). Element-specific microtomographic imaging of Drosophila brain stained with high-Z probes. J. Synchrotron Radiation 15(4), 374-377. DOI PubMed pdf
• *Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Masami Ohyama, Susumu Takekoshi, R. Yoshiyuki Osamura and Yoshio Suzuki (2008). Three-dimensional microtomographic imaging of human brain cortex. Brain Res. 1199, 53-61. DOI PubMed arXiv
• *Ryuta Mizutani, Akihisa Takeuchi, Tomohiro Hara, Kentaro Uesugi and Yoshio Suzuki (2007). Computed tomography imaging of the neuronal structure of Drosophila brain. J. Synchrotron Radiation 14(3), 282-287. DOI PubMed
• *Ryuta Mizutani, Tomohiro Hara, Akihisa Takeuchi, Kentaro Uesugi and Yoshio Suzuki (2006). Microtomographic analysis of Drosophila brain. Biophysics (Seibutsu Butsuri) 46(suppl 2), S388. DOI pdf
• Yasuhiro Anraku, Ryuta Mizutani, and Yoshinori Satow (2005). Protein splicing: its discovery and structural insight into novel chemical mechanisms. IUBMB Life 57(8), 563-574. Review. PubMed
• Ryuta Mizutani, Yasuhiro Anraku, and *Yoshinori Satow (2004). Protein splicing of yeast VMA1-derived endonuclease via thiazolidine intermediates. J. Synchrotron Radiation 11(1), 109-112. PubMed PDB1UM2 pdf
• Umeharu Ohto, Ryuta Mizutani, Mitsuaki Nakamura, Hideki Adachi, and *Yoshinori Satow (2004). Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor. J. Synchrotron Radiation 11(1), 105-108. PubMed PDB1UJ3
• Ryuta Mizutani, Yoshinori Satow, and Yasuhiro Anraku (2004). Discovery, analysis and chemical mechanism of protein splicing. プロテインスプライシング反応の化学機構. Tanpakushitsu Kakusan Koso 蛋白質 核酸 酵素 49(1), 18-27. PubMed pdf [Invited review, Japanese]
• Satoru Nogami, Tomoyuki Fukuda, Yuri Nagai, Shizu Yabe, Masako Sugiura, Ryuta Mizutani, Yoshinori Satow, Yasuhiro Anraku, and *Yoshikazu Ohya (2002). Homing at an extragenic locus mediated by VDE (PI-SceI) in Saccharomyces cerevisiae. Yeast 19(9), 773-782. PubMed
• Ryuta Mizutani, Satoru Nogami, Masato Kawasaki, Yoshikazu Ohya, Yasuhiro Anraku, and *Yoshinori Satow (2002). Protein-splicing reaction via a thiazolidine intermediate: crystal structure of the VMA1-derived endonuclease bearing the N- and C-terminal propeptides. J. Mol. Biol. 316(4), 919-929. PubMed PDB1JVA preprint
• Ken Murase, Ryuta Mizutani, and *Yoshinori Satow (2001). Expression, characterization and crystallization of the Fv fragment of mouse antibody 3B62 from the secondary immune response. Acta Crystallographica D57(11), 1703-1705. PubMed
• Hideshi Yokoyama, Ryuta Mizutani, *Yoshinori Satow, Yasuo Komatsu, Eiko Ohtsuka, and Osamu Nikaido (2000). Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation. J. Mol. Biol. 299(3), 711-723. PubMed PDB1EHL PDB1KEG
• Hideshi Yokoyama, Ryuta Mizutani, and *Yoshinori Satow (2000). Complex formation of double-stranded DNA (6-4) photoproducts and anti-(6-4) photoproduct antibody Fabs. Nucleic Acids Sym. Series 44, 151-152. PubMed pdf
• Shunsuke Miyamoto, Ryuta Mizutani, *Yoshinori Satow, Masato Kawasaki, Yoshikazu Ohya, and Yasuhiro Anraku (1999). Recognition and cleavage of double-stranded DNA by yeast VMA1-derived endonuclease. Nucleic Acids Sym. Series 42, 197-198. PubMed pdf
• Hideshi Yokoyama, Ryuta Mizutani, *Yoshinori Satow, Yasuo Komatsu, Eiko Ohtsuka, and Osamu Nikaido (1999). Crystal structures of the 64M-2 and 64M-3 antibody Fabs complexed with DNA (6-4) photoproducts. Nucleic Acids Sym. Series 42, 267-268. PubMed pdf
• *Ryuta Mizutani (1997). Structural basis of antigen-antibody recognition. 抗体の抗原特異性と三次元構造. Rinsho Meneki 臨床免疫 29(4), 490-495. National Diet Library Digitized Contents [invited, Japanese]
• Ryuta Mizutani, Keiko Miura, Tomonori Nakayama, Ichio Shimada, Yoji Arata, and *Yoshinori Satow (1996). Crystallization and crystallographic studies on Fab fragments of anti-nitrophenol antibodies from primary and secondary immune responses. J. Crystal Growth 168, 253-259. DOI
• Ryuta Mizutani, Keiko Miura, Tomonori Nakayama, Ichio Shimada, Yoji Arata, and *Yoshinori Satow (1995). Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate. J. Mol. Biol. 254(2), 208-222. PubMed PDB1NGP PDB1NGQ
• Ryuta Mizutani, Chigusa Matsunaga, Tsutomu Kouyama, Mamoru Sato, Yukiteru Katsube, Koichi Kato, Ichio Shimada, and *Yoji Arata (1993). Molecular structural studies of effector functions of a mouse immunoglobulin G that lacks the entire CH1 domain: small-angle X-ray scattering, nanosecond fluorescence depolarization and stable isotope-aided NMR analyses. Mol. Immunol. 30(18), 1665-1669. PubMed
• Ryuta Mizutani, Takako Igarashi, Toshiyuki Tanaka, Ichio Shimada, and *Yoji Arata (1993). Effector functions of a mouse IgG that lacks the entire C_H1 domain: C1q binding and complement fixation in the absence of antigen. J. Immunol. 150(1), 131-138. PubMed
• *Ryuta Mizutani (1993). Recongnition of phosphorylated tyrosine by the SH2 domain. SH2ドメインによるリン酸化チロシンの認識機構. Farumasia ファルマシア 29(3), 285. pdf [Review, Japanese]
• Ryuta Mizutani, Ichio Shimada, Yukio Ueno, Masafumi Yoda, Hiromichi Kumagai, and *Yoji Arata (1992). A ¹H-NMR study of the solution conformation of cyclo(GRGDSPA): conformational effects on the physiological activity. Biochem. Biophys. Res. Commun. 182(2), 966-973. PubMed
• *Ryuta Mizutani (1985). Undefined instructions of 6809 microprocessor. 6809の未定義命令. I/O 10(5), 286-287. (PDF is available upon request) [Japanese]

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